Pediculus humanus capitis, also known as head lice, is a disease that is still categorized as an overlooked disease, and is still commonly found throughout the world, especially in developing and poor countries. The purpose of this study is to develop behavioral models and Planned Behavior Theory for prevention of pediculus humanus capitis orphanages in Palembang, south sumatera (Indonesia). Method: The type of this research is an explanatory survey with a cross-sectional design. The population is the children of orpanages in Palembang which is in August 2022. The total sampling in this study are 211 children that collected from 12 orphanages located in 12 sub-districts within the city of Palembang, South Sumatra (Indonesia). The data collected using questionnaires were then analyzed using PLS (partial least squares), and added with the results of focus group discussions (FGD). Results: proposed models with significant pathways between modifying factor pathways to behavioral beliefs, normative beliefs, and control beliefs. Normative pathways to intention, control beliefs to intention, and the intention path to behavior (practice). There is one non-significant path between the Behavioral belief pathways to intention. Conclusion: improvement in behavior for prevention of pediculus humanus capitis can be done by observing normative beliefs with adhering to the advice of parents by not lending personal items, belief control factor with diligently changing bedding, and keeping the environment clean and comfortable, intention with increasing the desire of female students to clean the bed by changing bed pads and pillows regularly. Normative pathways to intention, control beliefs to intention, and the intention path to behavior (practice). There is one non-significant path between the Behavioral belief pathways to intention.