We also published a series of reviews in the current study investigating whether detox diets include the use of herbal extracts and probiotics is helpfull for treating breast cancer with the formulation of kefir. The results of this study may serve as a novel paradigm for future herbal medicine research, especially about the development of a novel anticancer agent. Only a limited number of wellcontrolled pre-clinical and clinical trials are reporting the potential value of detox. However, with very few formulations, insufficient animal models and randomized controlled trials have been rigorously tested. Thus, these findings support the possible detox diet role in reducing the breast cancer among the women if Saudi Arabia.