The effects of C. sinensis L. (Camellia sinensis L.) and its extracts on lipid profile are controversial. Plant and their products have been extensively used in the management of dyslipidemia and many plantbased anti-lipidemic products have least toxicity and can be used safely. The aim of current study is to evaluate lipid protective effects of interperitoneally induced n-Hexane, ethyl acetate, methanol, and water extracts of partially-processed leaves of C. sinensis L. (25mg/ml/kg b.w.) against streptozotocininduced (55mg/ml/kg b.w.) hyperlipidemic albino rats of both genders (300- 400 g), by keeping negative control groups as STZ and high fed diet induced hyperlipidemic, while metformin (250 mg/ml/kg b.w.) treated group was kept as a positive control, for the estimation of total cholesterol (TC), HDL, LDL and VLDL cholesterols, and triglycerides by kit methods. Statistically analyzed results (at p≤ 0.05) showed that C. sinensis leaves extracts have protective effect on lipid profile as total cholesterol (54.50 ± 9.40 mg/dL), triglycerides (53.00 ± 8.04 mg/dL), HDL (59.00 ± 20.58 mg/dL), LDL (23.33 ± 4.72 mg/dL), VLDL (14.50 ±1.29 mg/dL) were significantly less than negative control {total cholesterol (95.25 ± 10.47 mg/Dl), triglycerides (87.00 ± 5.72 mg/dL), HDL (57.00 ± 10.36 mg/dL), LDL (28.75 ± 5.56 mg/dL and VLDL (13.25 ± 1.71 mg/dl)} and high fed diet treated group {total cholesterol (310.00 ± 30.54 mg/dL), triglycerides (250.25 ± 57.71 mg/dL), HDL (56.75 ± 5.38 mg/dL), LDL (95.25 ± 19.92mg/dL) and VLDL (40.25 ± 1.71 mg/dL)} while results of plant extracts were near to positive control group {total cholesterol (65.50 ± 19.94 mg/dL), triglycerides (97.50 ± 32.65 mg/dL), HDL (46.50 ± 11.96 mg/dL), LDL (40.25 ± 26.81mg/dL), and VLDL (19.25 ± 9.32 mg/dL). Active compound from active extract can be isolated for the synthesis of its analogue or for the synthesis of new drugs to cure hyperlipidemic disorders.