This study seeks to clarify the relationship between the role of human resources management practices in achieving total quality in health centers in the northern sector, and to provide a systematic perception of the most important practices related to human resources that affect achieving total quality. It is represented in the quality of service in health centers in the northern sector through (employee relations, training and development, motivation, guidance and guidance). This has affected the improvement of the performance of workers in health centers and the satisfaction of service recipients. The study population formed all medical staff (service providers) in the health centers in the directorates of the northern sector of the Ministry of Health, and this information was taken from the directorates of health of Irbid governorate, and a sample of workers in all centers of the northern sector amounted to (100), and all of them were considered valid for analysis. The findings of this study showed that there is an average impact of training and development of workers in achieving total quality in health centers in Irbid Governorate, but it did not reach the level of statistical significance. While the impact of the employee's relations in achieving total quality was high, the study also showed that incentives have a clear motivation to improve total quality, and there is an average but not statistically significant impact of the element of guidance and guidance in achieving total quality in health centers in Irbid Governorate. In conclusion, this study concluded with a set of recommendations, which were drawn in light of the results, the most important of which was, conducting training courses to develop workers and increase their efficiency to achieve total quality in health centers. And Provide guidelines to enhance the efficiency of performance and quality of work for new employees.