Lean management is a method of managing and organizing work with the aim of improving a company's performance, particularly the quality and profitability of its production processes. This method relies heavily on a management strategy that allows employees to work in the best possible conditions. Aim: This study aimed to assess nurses’ knowledge regarding lean management principles, techniques, and concepts at King Khalid Hospital, Najran, Saudi Arabia. Design descriptive design was utilized in this study. Setting: The study was conducted in at King Khalid Hospital, Najran, Saudi Arabia. Sample: a convenient sample of nurses who work at the previously selected intensive care units. The total number of participants were (50) nurses. Tools: 1) Personal and work-related characteristics, 2) lean management knowledge questionnaire used to measure participants' lean management knowledge. Results: all participants had low mean scores in total lean management knowledge dimensions. Conclusion: The findings revealed that nurses had inadequate knowledge regarding lean management principles, techniques, and concepts, indicating the need for structured educational interventions to improve lean implementation in healthcare settings. Recommendations: hospital administrators should conduct educational program about lean management to raise nurses’ awareness regarding importance of applying lean methods in different healthcare settings to maximize their benefits for patients, organization and health care providers.