Large-scale urban regeneration has become increasingly difficult to manage through conventional design-centered approaches. Contemporary regeneration programs combine architectural design, engineering integration, regulatory approval, construction sequencing, stakeholder negotiation, quality control, and long-term urban objectives within project environments characterized by strong interdependencies. As project scale increases, failures at the interfaces between these activities can generate design conflicts, approval delays, construction rework, fragmented decision-making, and loss of continuity between planning and implementation. The central challenge is therefore not simply the management of individual project activities, but the coordination of relationships among them throughout the development lifecycle. This study develops an Intelligent Coordination Framework (ICF) for large-scale urban regeneration projects. The framework conceptualizes coordination as an architectural and managerial capability through which information, technical disciplines, regulatory processes, construction activities, and stakeholder decisions are integrated into a coherent project system. It is structured around five interconnected dimensions: Integrated Planning, Interdisciplinary Coordination, Regulatory and Construction Management, Project Monitoring and Quality Assurance, and Continuous Learning and Project Improvement. Rather than treating digitalization as an independent solution, the framework positions Building Information Modeling (BIM), shared information environments, and project management technologies as enabling infrastructures whose effectiveness depends on professional judgment, clearly structured responsibilities, and coordinated decision processes. This distinction is particularly important because research on collaborative urban regeneration similarly identifies stakeholder coordination and decision-making as persistent challenges, while BIM research demonstrates the value of integrated information environments for interdisciplinary coordination. The proposed framework extends architectural practice beyond the traditional boundaries of design by positioning architects and project teams as integrators of technical, organizational, and regulatory relationships. It further connects project coordination with governance, risk anticipation, construction quality, and organizational learning. The study contributes a systems- oriented perspective to urban regeneration research and provides a practical conceptual structure for architects, developers, project managers, contractors, consultants, and public authorities seeking to improve the delivery of complex large-scale developments.