The implanted port catheter is a device that is placed under the skin, it uses when intravenous therapy is needed for a long time as chemotherapy. Several complications are possible when using the implanted port catheter. The role of nurse is important to begin caring of patient with implanted port undergoing
chemotherapy, and the self-learning package is designed to help nurses understand practice. Aim: The aim of this study was evaluated effect of self-learning package to assess nurses' performance (knowledge& practice) for caring of patients with implanted port undergoing chemotherapy. Research
design: A quasi-experimental design research design was utilized to meet the aim of the study. Setting: The study was conducted at the oncology department in El-Demerdash Hospital affiliated to Ain Shams University. Study subject: A convenience sample of all available (30) nurses working in the previously mentioned unit within 6 months. Tools: two tools were used including: I- Self-administered questionnaire: it used to assess nurses’ knowledge and demographic characteristics of the study nurses. II-Nurses’ performance observational checklist: it used to assess nurses’ practice in caring of patients
with implanted port undergoing chemotherapy. Results & Conclusion: more than three quarters of nurses had inadequate practice, and more than half of them had inadequate knowledge regarding caring of patients with implanted port undergoing chemotherapy. Recommendations: Further research are recommended periodically to further study to be carried out in different settings on a larger sample for a wider utilization of the SLP, in order to achieve generalization of the results.