Emulgel is a new technology in revolutionary drug delivery system that allows for controlled release of emulsion and gel for topical application. When an emulsion is mixed into a gel, it becomes more stable. Luliconazole is a lipophilic antifungal medication that has been used to treat dermatophyte infections. The purpose of this work was to construct and characterize an Emulgel of an Antifungal Luliconazole formulation in order to combine hydrophobic or weakly water soluble drugs into formulations and administer them via gels, increasing drug skin penetration. The goal of this study was to generate Luliconazole emulgel formulations employing several types of gelling agents, such as carpool 940. The optimum Nano-emulgel consisted of Oil, Smix, and water at a ratio of (10: 35: 50), and it exhibited transmittance of 100%, solubility of Luliconazole 18.74± 0.24 mg/mL in n-octanol, globule size of 135±6.4 nm. The in vitro Luliconazole released from Nanoemulsion was 90.54 ± 2.6%, respectively. Ex vivo permeation was sustained during 12 h up to 63.95 ± 4.7%. All formulations were subjected to in-vitro diffusion tests. Color, homogeneity, consistency, pH, viscosity, spread ability, extrudability, and drug content, among other parameters, were all acceptable in all gels. Carpool 934- containing formulation with good spread ability, homogeneity, and soothing properties. In all of these aspects, the formulation F5 met all of the emulgels pharmaceutical parameters and appeared to be a good topical agent.